CLINICAL

CARDIOVASCULAR

• FICK_FORMULA
  • Cardiac output CO (L/min) = VO2 / ((SaO2 - SvO2) × Hb × 13.4)
  • Cardiac index CI (L/min/m²) = CO / BSA
  • Stroke volume SV (mL/beat) = (CO / HR) × 1000

SCAI Shock Stage Classification

• based on: https://www.jacc.org/doi/10.1016/j.jacc.2022.01.018

GASTROINTESTINAL

• Model for End-Stage Liver Disease (MELD)
  • cf. https://github.com/MIT-LCP/mimic-code/blob/main/mimic-iv/concepts/organfailure/meld.sql

RENAL

• URINE_OUTPUT
  • Urine output per time window

Acute Kidney Injury (KDIGO AKI)

• NOTE: updated guidelines are in the works, may change in medium to near future
• based on: KDIGO 2012 Clinical Practice Guideline for Acute Kidney Injury
• different Urine output definitions available cf. https://doi.org/10.1093/ndt/gfq332
  • consecutive (UO1): UO <0.5 mL/kg/h for at least 6 consecutive hours
  • any_period (UO2): UO <3 mL/kg during any 6h period
  • fixed_block (UO3): UO <3 mL/kg during a 6h fixed block (e.g. 6am–12pm)

estimated Glomerular Filtration Rate (eGFR)

• CKD Epidemiology Collaboration (CKD-EPI) equations (2021 version)
  • serum creatinine-based
  • (serum creatinine- and cystatin C-based)
• Modification of Diet in Renal Disease (MDRD) equation
• Cockcroft-Gault equation for creatinine clearance

RESPIRATORY

• ALVEOLAR_ARTERIAL_GRADIENT
  • PAO2 (alveolar oxygen partial pressure, calculated using the alveolar gas equation)
  • A-a gradient (difference between alveolar and arterial oxygen partial pressure)